The science

The actives are real.
The research is older than we are.

Lion's mane and cordyceps aren't trendy — they're two of the most-studied functional mushrooms in modern literature, with hundreds of peer-reviewed papers between them.

We don't invent claims. We cite them. Every active on our label is there because the research says it should be.

How it works

Three mechanisms, in plain English.

01 / Neurogenesis

Lion's Mane → NGF.

Hericenones and erinacines (compounds unique to lion's mane fruiting bodies) cross the blood-brain barrier and stimulate Nerve Growth Factor — the signal your brain uses to build new neurons and reinforce existing synapses.

02 / Oxygen uptake

Cordyceps → ATP.

Cordycepin (3'-deoxyadenosine) is structurally similar to adenosine and increases cellular ATP production. The practical effect: your muscles extract more usable energy from the same breath of oxygen.

03 / Immune modulation

Beta-glucans → Receptors.

Beta-1,3/1,6-D-glucans bind to Dectin-1 and CR3 receptors on your immune cells, priming them without over-activating them. This is why mushroom extracts are called 'adaptogenic' — they regulate up OR down depending on what the body needs.

The receipts

Selected peer-reviewed research.

2024 ✓ Peer-reviewed
Molecules (PubMed)

"Dietary Hericium erinaceus promotes structural and functional recovery of hippocampal neurons, with measurable improvements in memory and reductions in neuroinflammation."

Neuro-structure · Memory Study 01
Read on PubMed ↗
2023 ✓ Peer-reviewed
Nutrients (PMC)

"Lion's Mane supplementation produced statistically significant improvements in cognitive performance on validated assessments in healthy adults."

Cognition Study 02
Read on PubMed ↗
2024 ✓ Peer-reviewed
PubMed / Neurobiology

"Hericium erinaceus compounds stimulate adult neurogenesis — the growth of new neurons — through NGF-pathway activation."

Neurogenesis Study 03
Read on PubMed ↗
2017 ✓ Peer-reviewed
Journal of Dietary Supplements

"Cordyceps militaris improved physical performance markers in healthy adults after a three-week supplementation protocol."

Performance Study 04
Read on PubMed ↗
2012 ✓ Peer-reviewed
J. of Alt. & Comp. Medicine

"Cordyceps supplementation improved exercise performance and tolerance in healthy older adults, with no adverse events reported."

Endurance Study 05
Read on PubMed ↗
2006 ✓ Peer-reviewed
J. of Alt. & Comp. Medicine

"Cordyceps Cs-4 supplementation raised VO2 max and metabolic threshold in healthy elderly subjects — a direct measure of oxygen utilisation."

VO2 Max · Oxygen Study 06
Read on PubMed ↗

These statements have not been evaluated by the FDA. Our products are not intended to diagnose, treat, cure, or prevent any disease. Full citations and lab reports available on request.

Batch G225K2002 · Certificate of Analysis

Every batch. Every time.

Download full COA (PDF) ↗
Batch G225K2002 Mfg 2025-11-20 Analysis 2025-11-22 Report (2025)CBBZ № 0000533
TestSpecificationStandardResult
Lead (as Pb) ≤ 0.5 mg/kg GB 2762 Conform
Arsenic (as As) ≤ 0.5 mg/kg GB 2762 Conform
Loss on Drying ≤ 18.0 g/100g SB/T 10021 7.90
Reducing Sugars ≤ 0.5 g/100g SB/T 10021 0.32
Total Plate Count n=5 · m=10,000 CFU/g SB/T 10021 <10 across all
Yeast & Mold ≤ 50 CFU/g GB 4789.15 Conform
Coliforms n=5 · m=10 CFU/g SB/T 10021 <10 across all
Staphylococcus aureus 0 / 25g GB 4789.10 Conform
Salmonella 0 / 25g GB 4789.4 Conform

Conclusion: Complies with specification · Report dated 2025-11-25.

Lion's Mane fruiting body — cross-section
What to look for on a label

Fruiting body. Not mycelium.

When you see "mushroom extract" on a supplement, it almost always means mycelium grown on grain — basically mushroom roots in sawdust — not the fruiting body you'd recognise as an actual mushroom.

The hericenones and erinacines that make Lion's Mane worth taking are found in fruiting-body extract only. Cordycepin, the active molecule in Cordyceps, follows the same pattern.

Every Seren product is 100% fruiting-body extract. Always has been. Always will be.

Dual-extracted. Twice the actives.
Our process

Dual-extracted. Twice the actives.

Pass 01 — Hot water. Draws out the water-soluble beta-1,3/1,6-D-glucans that prime your immune receptors. This is the pass most brands stop at.

Pass 02 — Food-grade ethanol. Pulls the fat-soluble terpenes and sterols — including hericenones and cordycepin — that hot water leaves behind. Evaporated off before bottling.

20:1 ratio. Twenty kilos of fruiting body condensed into one kilo of finished extract. The potency lives in that ratio.

The mushroom dictionary

Two mushrooms, two purposes.

A quick reference. Every mushroom we use, what it's for, and the extract ratio you should expect on a label worth buying.

Lion's Mane

20:1 extract

For cognitive function, focus, and nerve support.

Shop Lion's Mane →

Cordyceps

10:1 extract

For energy, endurance, and oxygen utilisation.

Shop Cordyceps →
Our commitment

The Seren Standard.

0g Added Sugar

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We've carefully balanced flavour profiles so no added sugar is needed. We use natural fruit juices for the lead flavour.

Up to 3,000mg of Mushrooms

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Our gummies are jam-packed with mushrooms — up to 10× the amount in most other brands.

20 Calories or Less

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Every serving comes in at 20 calories or fewer. The Lion's Mane Focus Gummies are only 15 calories per serving.

100% of Your Daily Vitamins

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Enriched with essential vitamins to support your focus, energy, and nervous system — 100% of your recommended daily intake in two gummies.

Vegan

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We use pectin — derived from the skin of citrus fruits — as our gelling agent.

Real Fruit Juice

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We use natural flavours from real fruit to create the delicious, juicy taste — no artificial sweeteners or colours.

Ready to feel it?

The science is interesting. The experience is better. Two pouches, thirty-day money-back guarantee.

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